Abstract：Objective: To investigate the correlation between Helicobacter pylori and digestive tract diseases and analyze the risk factors. Methods: The medical records of 2110 and 1247 patients who underwent gastroscopy and colonoscopy in Oriental Hospital of Beijing University of Traditional Chinese Medicine from January 2020 to December 2023 were retrospectively analyzed, and the subjects were divided into the helicobacter pylori positive group and the negative group according to the results of helicobacter pylori detection. Results: The infection rates of Helicobacter pylori in patients with reflux esophagitis, esophageal cancer, chronic atrophic gastritis, gastric ulcer, duodenal ulcer, complex ulcer, gastric polyp and gastric cancer were 73.05%, 81.08%, 77.67%, 86.77%, 82.70%, 91.67%, 68.28% and 77.78%, respectively. There was a significant difference between the infected group and the uninfected group (P<0.05). Among them, the infection rate of Helicobacter pylori in patients with colorectal polyps was 77.80%, and the difference between the infected group and the uninfected group was significant (P<0.05). The infection rates of Helicobacter pylori in patients with chronic atrophic gastritis and colorectal polyps, peptic ulcer and colorectal polyps, gastric polyps and colorectal polyps, gastric cancer and colorectal polyps were 73.23%, 79.61%, 73.37%, and 92.31%, respectively. The infection rate of the infected group was significantly higher than that of the uninfected group (P<0.05). Gender, age, and marital status were independent risk factors for H. pylori infection (P<0.05). Conclusion: Helicobacter pylori infection is closely related to upper and lower digestive tract diseases and complications. In addition, being married and advanced age may be independent risk factors for H. pylori infection. This is essential for the management of Helicobacter pylori infection as well as the treatment and prevention of gastrointestinal disorders.
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2025, Vol. 31 
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