Abstract：Objective: To explore the effect of hyperuricemia (HUA) on microvascular disease (MVD) in elderly patients with type 2 diabetes mellitus (T2DM). Methods: 102 patients with T2DM admitted to the hospital from January 2021 to January 2024 were selected. The detection rate of HUA was statistically analyzed. The patients were divided into MVD group and non-MVD group according to the presence/absence of MVD. The incidence of HUA, general data, and biochemical indicators were compared between the two groups. Multivariate logistic regression analysis was used to screen risk factors for MVD in elderly patients with T2DM. Results: The detection rate of HUA in this study was 73.53%. There were 72 patients with MVD and 30 patients without. Univariate analysis showed that the proportions of patients with HUA and hypertension were significantly higher in the MVD group than in the non-MVD group. The inter-group differences in body mass index (BMI), course of disease and triglyceride were statistically significant (P<0.05). Multivariate logistic regression analysis showed that HUA, BMI, hypertension, and triglyceride were risk factors for MVD in elderly patients with T2DM (P<0.05). Conclusion: HUA is also one of the risk factors for MVD in elderly patients with T2DM. In addition, the relationship between BMI, hypertension, triglyceride and MVD in elderly patients with T2DM deserves clinical attention.
刁欣晨, 王思宏, 宋全超. 高尿酸血症对老年2型糖尿病患者微血管病变的影响[J]. 河北医学, 2025, 31(8): 1322-1326.
DIAO Xinchen, WANG Sihong, SONG Quanchao. Effect of Hyperuricemia on Microvascular Disease in Elderly Patients with Type 2 Diabetes Mellitus. HeBei Med, 2025, 31(8): 1322-1326.
2025, Vol. 31 
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