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| Effect of Shenmai Injection on Inflammatory Factors in Patients with Severe Pneumonia |
| FAN Xiaochun, TU Su, CAO Futao |
| Wuxi Second People's Hospital Affiliated to Nanjing Medical University, Jiangsu Wuxi 214002, China |
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Abstract Objective: To observe the clinical effect of Shenmai injection on tumor necrosis factor-alpha(TNF-α), IL-1β, IL-6, IL-10 in patients with severe pneumonia.Methods: A total of 60 patients with severe pneumonia were divided into routine group (n=30) and observation group (n=30). Patients in the routine group were in routine therapy. Treatment of routine therapy combined with Shenmai injection was applied in the observation group. The clinical effect and the levels of TNF-α, IL-1β, IL-6, IL-10 were compared between the two groups. Results: The effective rate was higher in observation group than that of the routine group (P<0.05). The levels of TNF-α, IL-1β,IL-6 decreased significantly and the level of IL-10 increased after the treatment (P<0.05). The levels of TNF-α, IL-1β,IL-6 were significantly lower than those in the control group, while the level of IL-10 was significantly higher than that in the control group (P<0.05). Conclusion: Treatment of routine therapy combined with Shenmai injection for severe pneumonia has certain clinical application value.
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2018, Vol. 24 
