缺血预适应和侧枝循环对合并糖尿病的急性心肌梗死患者近期预后的影响

doi:10.3969/j.issn.1006-6233.2018.02.020

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Abstract Objective: To investigate the effects of myocardial ischemic preconditioning (IP) and coronary collateral circulation (CR) on the short-term prognosis of patients with acute myocardial infarction (AMI) complicated with diabetes mellitus. Methods: Retrospective analysis of diabetic patients with acute myocardial infarction in 115 cases, according to the 48 hours of pre infarction angina pectoris divided into ischemic preconditioning group (IP group, n=69) and non-ischemic preconditioning group (group NIP, n=46). The two groups were divided into subgroups (A group, B group, C group, D group) according to the collateral circulation (CR). The baseline data, myocardial infarct size, left ventricular ejection fraction and 6 months follow-up . The incidence of death, severe arrhythmia, left ventricular function and other adverse reactions were compared between the two groups. Results: The peak value of CK and CK-MB in group A were significantly lower than that in group D(P<0.05). The A in group LVEF was significantly higher than that in other groups(P<0.05). Incidence of adverse reactions of A group was lower than that of B group, C group, D group (P<0.05); B group, C group of patients with adverse reaction rate was significantly lower than that in D group, the difference was statistically significant (P<0.05). Conclusions: In patients with acute myocardial infarction complicated with diabetes mellitus, myocardial ischemic preconditioning and collateral circulation can play a protective role in myocardial infarction and improve the prognosis.

Key words： Myocardial ischemic preconditioning Acute myocardial infarction Collateral circulation

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2018.02.020 OR http://www.hbyxzzs.cn/EN/Y2018/V24/I2/255

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