大柴胡汤治疗急性盆腔炎的临床疗效及对患者血清分泌型免疫球蛋白A CRP的影响

doi:10.3969/j.issn.1006-6233.2021.02.032

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Abstract Objective: To investigate the clinical effect of Dachaihu Decoction on acute pelvic inflammation and its effect on serum secretory immunoglobulin A(sIgA) and C-reactive protein(CRP). Methods: 144 patients with acute pelvic inflammatory disease from December 2018 to May 2020 were randomly divided into two groups, 72 cases in each group. The control group was treated with cefoxitin sodium and doxycycline hydrochloride. The observation group was treated with Dachaihu Decoction on the basis of the control group. The pelvic effusion, pelvic mass, serum inflammatory factors [CRP, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6)] and sIgA before and after treatment were compared between the two groups. The clinical efficacy and the occurrence of adverse reactions during treatment were recorded and compared between two groups. Results: The effective rate of treatment in the observation group was higher than that in the control group (97.22% vs.84.72%) (P<0.05). Compared with before treatment, the level of pelvic effusion and pelvic mass in the observation group and the control group after treatment were decreased (P<0.05), and the level of pelvic effusion and pelvic mass in the observation group was lower than that in the control group (P<0.05). The levels of CRP, TNF-α and IL-6 in the observation group after treatment were lower than those in the control group, and the levels of sIgA were higher than that in the control group (P<0.05). The rate of adverse reactions in the observation group during treatment was lower than that in the control group (8.33% vs 20.83%)(P<0.05). Conclusion: Dachaihu decoction has better clinical efficacy in the treatment of acute pelvic inflammation, reducing pelvic effusion and pelvic mass size, reducing body inflammatory factors and improving immune function, and reducing the adverse reactions, which is worthy of promotion.

Key words： Dachaihu decoction Acute pelvic inflammation Clinical efficacy Inflammatory factors Secretory immunoglobulin A

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	ZHANG Yamin
	ZHANG Liran
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Cite this article:

ZHANG Yamin,ZHANG Liran,et al. Clinical Effect of Dachaihu Decoction on Acute Pelvic Inflammation and its Effect on Secretory Immunoglobulin A and Serum CRP[J]. HeBei Med, 2021, 27(2): 326-330.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2021.02.032 OR http://www.hbyxzzs.cn/EN/Y2021/V27/I2/326

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