肾透明细胞癌的常规超声及超声造影声像图表现特征及鉴别诊断分析

doi:10.3969/j.issn.1006-6233.2023.07.012

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Abstract Objective: To investigate the characteristics and differential diagnostic value of conventional ultrasound and contrast-enhanced ultrasound in renal clear cell carcinoma (CCRCC). Methods: A total of 76 patients (CCRCC group) with CCRCC who were treated in our hospital from September 2020 to August 2022 were selected,including Fuhrman classification:48 cases of grade Ⅰ~Ⅱ and 28 cases of grade Ⅲ-Ⅳ.,and 50 patients with renal angiomyolipoma (RAML) who were treated at the same time were selected as the control group (RAML group).The differences between conventional ultrasound and contrast-enhanced ultrasound images of the two groups were compared,and the differences between conventional ultrasound and contrast- enhanced ultrasound images of CCRCC lesions with different Fuhrman grades were analyzed,as well as the diagnostic value of conventional ultrasound combined with contrast-enhanced ultrasound. Results: The diameter of lesions in CCRCC group was (35.54 ± 11.02) mm,which was significantly higher than that in RAML group (P<0.05).The proportion of hypoechoic,rich blood flow,"fast forward" perfusion,high perfusion intensity,uneven perfusion and peripheral annular enhancement in CCRCC group was 81.58%,57.89%,94.74%,93.42%,73.68% and 42.11% respectively,which was significantly higher than that in RAML group (P<0.05).Compared with grade Ⅰ~Ⅱ lesions,the diameter of grade Ⅲ ~Ⅳ lesions in CCRCC group was (41.25±10.03) mm,which was significantly higher (P<0.05).Compared with in grade Ⅰ~Ⅱ lesions,the percentage of peripheral annular enhancement in grade Ⅲ ~ Ⅳ lesions in CCRCC group was 56.25%,which was significantly higher (P<0.05).Compared with conventional ultrasound and contrast-enhanced ultrasound,the sensitivity of conventional ultrasound+ contrast-enhanced ultrasound in the diagnosis of CCRCC was 94.74%,which was significantly higher (P<0.05).The accuracy and negative predictive value of conventional ultrasound+ contrast- enhanced ultrasound in the diagnosis of CCRCC were 86.51% and 90.24%,respectively,which were significantly higher than those of conventional ultrasound (P<0.05).The accuracy of contrast-enhanced ultrasound in the diagnosis of CCRCC was 83.33%,which was significantly higher than that of conventional ultrasound (P<0.05). Conclusion: Compared with RAML,the image features of conventional ultrasound and contrast-enhanced ultrasound of CCRCC are different to some extent,the combination of conventional ultrasound and contrast-enhanced ultrasound has better application value in differential diagnosis of CCRCC.

Key words： Renal clear cell carcinoma Renal angiomyolipoma Contrast ultrasound Differential diagnosis

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2023.07.012 OR http://www.hbyxzzs.cn/EN/Y2023/V29/I7/1120

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