不同功率HoLEP联合钬激光碎石术在治疗良性前列腺增生合并膀胱结石的疗效及安全性分析

doi:10.3969/j.issn.1006-6233.2024.10.018

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Abstract Objective: To study the efficacy and safety of different powers of holmium laser enucleation of the prostate (HoLEP) combined with holmium laser cystolithotripsy (HLC) in the treatment of benign prostatic hyperplasia (BPH) with bladder stones. Methods: The clinical data of 110 patients with BPH combined with bladder stones admitted to Danyang People's Hospital from January 2019 to January 2024 were collected. According to the surgical methods, patients who received high-power HoLEP combined with HLC were included in the HP group (n=62), and patients who adopted low-power HoLEP combined with HLC were enrolled as the LP group (n=48). Perioperative indicators, urinary function, stress indicators, and postoperative complications were compared between both groups. Results: The surgical time, excised tissue mass, bladder irrigation time and postoperative urinary catheter retention time with (68.49±15.36) min, (41.42±10.59) g (1.86±0.66) d and (2.34±0.85) d in the HP group were not statistically different form (70.15±15.71) min, (42.81±9.93) g, (1.81±0.72) d and (2.58±0.92) d in the LP group (P>0.05). The time of glandular enucleation and hospital stay with (35.80±7.21) min and (3.62±0.64) d in the HP group were shorter than (41.64±7.83) min and (3.86±0.50) d in the LP group, and the enucleation efficiency and decrease rate of hemoglobin with (1.15±0.25) g/min and (8.05±1.58) g/L were higher than (1.02±0.18) g/min and (7.36±1.72) g/L in the LP group (P<0.05). At 3 months after surgery, the differences of Qmax, PVR and PSA before and after treatment were not statistically significant between the HP group and the LP group (P>0.05). The differences of SP, PGE2 and NE before and after treatment revealed no statistical differences between the HP group and the LP group at 24 hours after surgery (P>0.05). There was no statistical significance in incidence of postoperative complications between the HP group (12.88%) and the LP group (10.40%) (P>0.05). Conclusion: High-power and low-power HoLEP combined with HLC have similar efficacy in the treatment of BPH with bladder stones. High-power HoLEP has higher enucleation efficiency, and shorter glandular enucleation time and hospital stay, and low-power HoLEP has better hemostatic effect.

Key words： Low-power holmium laser enucleation of the prostate High-power holmium laser enucleation of the prostate Holmium laser cystolithotripsy Benign prostatic hyperplasia Bladder stones

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	XIA Dongdong
	ZENG Minghui
	QIN Suobing
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XIA Dongdong,ZENG Minghui,QIN Suobing, et al. Efficacy and Safety Analysis of Different Power HoLEP Combined with Holmium Laser Lithotripsy in the Treatment of Benign Prostatic Hyperplasia with Bladder Stones[J]. HeBei Med, 2024, 30(10): 1680-1684.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2024.10.018 OR http://www.hbyxzzs.cn/EN/Y2024/V30/I10/1680

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