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| Comparison of Analgesic and Rehabilitation Effects Between Lidocaine Aerosol and Injection Combined with Diclofenac Potassium Suppository in Pediatric Circumcision |
| XI Qi, JIANG Bin, ZHOU Xuewu, et al |
| Xuzhou Central Hospital, Jiangsu Xuzhou 221009, China |
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Abstract Objective: To compare the analgesic efficacy and rehabilitation quality of lidocaine aerosol combined with diclofenac potassium suppository versus lidocaine injection combined with diclofenac potassium suppository in pediatric circumcision. Methods: A total of 120 pediatric patients undergoing circumcision at our hospital from July 2020 to March 2024 were prospectively studied. Patients were divided into two groups: the aerosol group (n=60, lidocaine aerosol combined with diclofenac potassium suppository) and the injection group (n=60, lidocaine injection combined with diclofenac potassium suppository). Age, BMI, postoperative pain recovery time, and surgical duration were compared. Anesthesia onset time, FLACC (Face, Legs, Activity, Cry, Consolability) scores, VAS (Visual Analog Scale) scores, postoperative complications (bleeding, edema, infection), hospitalization time, and first urination time were evaluated. Results: There were no significant differences in age, BMI, postoperative pain recovery time, or surgical duration between the two groups (P>0.05). The aerosol group had a shorter anesthesia onset time compared to the injection group (t=-11.539, P<0.001). Repeated measures ANOVA revealed significant differences in FLACC scores between anesthesia methods, time points, and their interaction (P<0.05). The aerosol group had significantly lower FLACC scores at all time points (P<0.001), with pain increasing over time (P<0.05). The aerosol group also had fewer postoperative complications (bleeding, edema, infection) than the injection group (χ2=7.063, P<0.05). VAS scores showed significant differences between anesthesia methods, time points, and their interaction (P<0.05), with the aerosol group having lower VAS scores at all postoperative time points (P<0.001) and a continuous decline in scores (P<0.05). Additionally, the aerosol group had shorter hospitalization and first urination times compared to the injection group (P<0.001). Conclusion: Compared to lidocaine injection combined with diclofenac potassium suppository, lidocaine aerosol combined with diclofenac potassium suppository provides superior analgesia, better sedation, fewer postoperative complications, and shorter hospitalization and first urination times in pediatric circumcision.
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[1] 韩欣欣,汪璐璐,王子瑞,等.局部麻醉药物在儿童口腔诊疗中的应用[J].中华口腔医学研究杂志(电子版),2019,13(1):51-55.
[2] Diclofenac-potassium/serrapeptase[J].Reactions Weekly,2023,1983(1):174.
[3] 石秀全,陆龙伟,傅点.包皮环切术的研究进展及应用现状[J].中华男科学杂志,2023,29(6):557-561.
[4] Voepel Lewis T,Zanotti J,Dammeyer J.Reliability and validity of the face,legs,activity,cry,consolability behavioral tool in assessing acute pain in critically ill patients[J].American journal of critical care,2010,19(1).55-61.
[5] 孙兵,车晓明(整理).视觉模拟评分法(VAS)[J].中华神经外科杂志,2012,28(6):645.
[6] 张科,田广润,赵莹,等.青少年包皮过长和包茎与复发性泌尿系统感染的相关性调查[J].中国性科学,2022,31(5):5-8.
[7] 徐晓龙,张前进,刘红梅,等.一次性包皮环切缝合器改进手术方法在儿童包皮过长治疗中的应用[J].国际泌尿系统杂志,2020,40(4):656-659.
[8] Daniar O,Claudius H,Ahmed E,et al.Preputioplasty asa surgical alternative in treatment of phimosis[J].Internationaljournal of impotence research,2022,34(4):353-358.
[9] 徐珂,殷秋红,穆亚宁,等.利多卡因气雾剂与利多卡因注射液分别复合双氯芬酸钾栓对儿童包皮环切手术患者的镇痛效果比较[J].儿科药学杂志,2023,29(8):45-48.
[10] 刘向荣,宋少波,柳胜安,等.利多卡因气雾剂在阻塞性睡眠呼吸暂停综合征患者无痛胃镜中的应用[J].暨南大学学报(自然科学与医学版),2023,44(4):431-436.
[11] 李乐,范美娇,范栓琴,等.右美托咪定静脉泵注与利多卡因气雾剂气管导管和口腔喷洒在小儿龋齿治疗术中的应用观察[J].山东医药,2020,60(24):69-71.
[12] Nascimento D O G S,Alves F L,Castro A G G,et al.Physicochemical characterization of the gelatin/polycaprolactone nanofibers loaded with diclofenac potassium for topical use aiming potential anti-inflammatory action[J].International Journal of Polymeric Materials and Polymeric Biomaterials,2022,71(17):1303-1318. |
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2025, Vol. 31 
