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| Analysis of Manifestations of Prenatal Ultrasound Screening for Fetal Heart Abnormalities and Chromosomal Karyotype Abnormalities |
| CUI Zhihui, ZHAO Xuliang, WEI Zhuojun, et al |
| No.901 Hospital of Joint Logistics Support Force, Anhui Hefei 230031, China |
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Abstract Objective: To analyze the manifestations of prenatal ultrasound screening of fetal heart abnormalities and chromosomal karyotype abnormalities. Methods: The clinical data of 138 pregnant women at 16-32 weeks of pregnancy who were diagnosed with fetal heart malformations by ultrasound screening in the outpatient department of the hospital were retrospectively analyzed from January 2021 to August 2024.The fetal heart ultrasound results and chromosomal karyotype abnormalities manifestations were analyzed. Results: Among the 130 fetuses with abnormal heart manifestations suggested by ultrasound,there were 79 cases (57.25%) of single heart abnormalities,14 cases (10.14%) of single heart abnormalities with extracardiac abnormalities,26 cases (18.84%) of multiple heart abnormalities,15 cases (10.87%) of multiple heart abnormalities with extracardiac abnormalities,and 4 cases (2.90%) of arrhythmia.There were 59 cases (42.75%) with extracardiac abnormalities among 138 fetuses.There were 18 fetuses with abnormal karyotypes in chromosome examination.Among them,there were 7 cases with isolated strong echo of heart as the indication,3 cases with strong echo of heart combined with extracardiac abnormality as the indication,2 cases with double outlets of right ventricle,1 case with single ventricular septal defect,1 case with ventricular septal defect combined with other abnormalities,1 case with tetralogy of Fallot,1 case with right aortic arch,1 case with endocardial cushion defect and case with left ventricular dysplasia.The detection rate of chromosomal abnormalities in fetuses with multiple heart abnormalities complicated with extracardiac abnormalities was higher than that of a single heart abnormality. Conclusion: Prenatal ultrasound screening of fetal heart malformations is closely related to chromosomal karyotype abnormalities,which can provide a reliable basis for subsequent invasive examinations.When the fetus has multiple heart malformations,heart malformations with extracardiac malformations,invasive examinations should be performed as soon as possible to reduce the rate of birth defects.
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2025, Vol. 31 
