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| Analysis of Pathogenetic Features Drug Resistance and Risk Factors of Fungal Infections Complicating COPD |
| SUN Liying, JIANG Qi, PAN Ni, et al |
| Department of Family Medicine, Guiyang Hospital, Guizhou Guiyang 550009, China |
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Abstract Objective: To investigate the pathogenic features, drug resistance and risk factors for fungal infections in patients with chronic obstructive pulmonary disease (COPD). Methods: The etiology and clinical data of COPD patients who were treated in our hospital from March 2022 to March 2024 were selected and analyzed. Results: A total of 84 strains of pathogenic bacteria were isolated from 62 patients with COPD complicated with fungal infection, including Candida albicans (41.67%), Candida tropicalis (22.62%) and Aspergillus fumigatus (14.29%). Pathogenic bacteria had good sensitivity to voriconazole and fluconazole. Age, course of disease, hypoproteinemia, hormone use time and invasive operation were independent influencing factors of fungal infection complicating COPD patients. Conclusion: The invasive strains of COPD patients with fungal infection are extensive and have certain drug resistance. The occurrence of infection is related to age, course of disease, hypoproteinemia, hormone use time and invasive operation. Paying attention to the pathogenic characteristics, drug resistance and risk factors of fungal infection, and taking timely intervention measures can help improve the quality of life of COPD patients.
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2025, Vol. 31 
