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| Effects of Platelet-Rich Fibrin on Guided Bone Regeneration during Maxillary Anterior Tooth Implantation and the Impact on Dental Function |
| LI Sensen, ZHU Bin, HUANG Jing, et al |
| The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Hubei Enshi 445000, China |
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Abstract Objective: To observe the effects of platelet-rich fibrin (PRF) on guided bone regeneration during maxillary anterior tooth implantation and the impact on dental function. Methods: A total of 102 patients who underwent maxillary anterior tooth implantation in the hospital between January 2021 and December 2023 were selected and randomly assigned to the traditional group (51 cases) and the experimental group (51 cases) by drawing lots. For the traditional group, absorbable collagen membrane combined with Bio-Oss bone powder was used for guided bone regeneration during surgery. For the experimental group, PRF was used for guided bone regeneration during surgery. The two groups were compared on postoperative pain, success rate of implantation, mucosa healing on day 7 after surgery, bone regeneration effect 6 months after surgery, dental function, and aesthetic effect. Results: The success rates of implantation in the two groups were close (P>0.05). Postoperative pain grading results in the experimental group were better than those in the traditional group (P<0.05). The experimental group obtained better mucosa healing and bone regeneration as compared with the traditional group (P<0.05). The scores for dental function in various dimensions of the experimental group were higher as compared with the traditional group (P<0.05). The pink aesthetic score (PES) and white aesthetic score (WES) of the experimental group were better than those of the traditional group (P<0.05). Conclusion: Applying PRF guided bone regeneration during maxillary anterior tooth implantation can promote mucosa healing and bone regeneration while alleviating postoperative pain and improving aesthetic effects and dental function.
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2025, Vol. 31 
