扩张型心肌病心律失常老年患者心源性猝死发生的影响因素及其预测价值分析

doi:10.3969/j.issn.1006-6233.2025.09.020

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Abstract Objective: To explore the influencing factors and predictive value of sudden cardiac death (SCD) in elderly patients with arrhythmogenic dilated cardiomyopathy (AR-DCM). Methods: A total of AR-DCM patients diagnosed at our hospital from January 2022 to January 2025 were selected as the subjects of this study, and divided into non-SCD group (n=142) and SCD group (n=52) based on whether SCD occurred. Univariate analysis was performed on patients' clinical data, tests, and electrocardiographic examination data; Spearman correlation analysis was used to assess the correlation between each indicator and the occurrence of SCD; multivariate binary Logistic regression analysis was conducted to identify the influencing factors of SCD in elderly AR-DCM patients; and ROC curve analysis was used to evaluate the predictive value of the relevant indicators. Results: The proportion of NYHA Class Ⅲ and Ⅳ in elderly AR-DCM patients with SCD, as well as the levels of cTnT and NT-proBNP, and the duration of Tp-Te and Tc were higher in patients without SCD (P<0.05), but only the level of NT-proBNP was an independent influencing factor (P<0.05), and had a high predictive value (AUC=0.965). Conclusion: The level of NT-proBNP is an independent influencing factor for the occurrence of SCD and has the best predictive value.

Key words： Dilated cardiomyopathy Arrhythmia Sudden cardiac death Influencing factors Predictive value

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2025.09.020 OR http://www.hbyxzzs.cn/EN/Y2025/V31/I9/1525

[1] Harding D,Chong M H A,Lahtoi N,et al.Dilated cardiomyopathy and chronic cardiac inflammation:pathogenesis,diagnosis and therapy[J].Intern Med,2023,293(1):23-47.
[2] Yang J,Lv T,Zhou J,et al.The effect of ivabradine therapy on dilated cardiomyopathy patients with congestive heart failure:a systematic review and meta-analysis[J].Frontiers in Cardiovascular Medicine,2023,10(1):1149351.
[3] Reza N,De Feria A,Chowns J L,et al.Cardiovascular characteristics of patients with genetic variation in desmoplakin (DSP)[J].Cardiogenetics,2022,12(1):24-36.
[4] Pooranachandran V,Nicolson W,Vali Z,et al.Non-invasive markers for sudden cardiac death risk stratification in dilated cardiomyopathy[J].Heart (British Cardiac Society),2022,108(13):998-1004.
[5] Arbelo E,Protonotarios A,Gieno J R,et al.2023 ESC Guidelines for the management of cardiomyopathies[J].European Heart Journal,2023,44(37):3503-3626.
[6] Yang R,Yu J,Luo C,et al.Correlations and consistency of body composition measurement indicators and BMI:a systematic review[J].International Journal of Obesity,2025,49(1):4-12.
[7] Konemann H,Dagres N,Merino J L,et al.Spotlight on the 2022 ESC guideline management of ventricular arrhythmias and prevention of sudden cardiac death:10 novel key aspects[J].Europace:European pacing,arrhythmias,and cardiac electrophysiology:journal of the working groups on cardiac pacing,arrhythmias,and cardiac cellular electrophysiology of the European society of cardiology,2023,25(5):91.
[8] Wang L,Wang Y,Wang J,et al.Myocardial activity at (18)F-FAPI PET/CT and risk for sudden cardiac death in hypertrophic cardiomyopathy[J].Radiology,2023,306(2):221052.
[9] Li X,Dai L,Zhang J.Case Report:Mutation in TNNI3(c.544G>A):a novel likely pathogenic mechanism of neonatal dilated cardiomyopathy[J].Frontiers in Pediatrics,2023,11(1):1291609.
[10] De Angelis G,Merlo M,Barbati G,et al.Longitudinal arrhythmic risk assessment based on ejection fraction in patients with recent-onset nonischemic dilated cardiomyopathy[J].Journal of the American Society of Echocardiography:Official Publication of the American Society of Echocardiography,2022,35(8):801-809.
[11] Oommen S G,Man R K,Talluri K,et al.Heart failure with improved ejection fraction:prevalence,predictors,and guideline-directed medical therapy[J].Cureus,2024,16(6):61790.
[12] Sourour N,Riveland E,Nesgaard P,et al.Associations between biomarkers of myocardial injury and systemic inflammation and risk of incident ventricular arrhythmia[J].JACC:Clinical Electrophysiology,2024,10(9):2021-2032.
[13] 殷梦,李子进.B型钠尿肽和N末端B型钠尿肽前体对老年慢性阻塞性肺疾病合并心力衰竭的诊断价值[J].中华老年心脑血管病杂志,2024,26(9):1020-1025.