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| Relationship of Red Blood Cell Distribution Width and Hematocrit Level with qSOFA Score in Elderly Patients with Upper Gastrointestinal Bleeding and Evaluation Value on Prognosis |
| WANG Qiuyue, XIE Faping, ZHOU Renzheng, et al |
| Chuzhou First People's Hospital, Anhui Chuzhou 239000, China |
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Abstract Objective: To observe the changes of red blood cell distribution width (RDW) and hematocrit (Hct) in elderly patients with upper gastrointestinal bleeding (UGB), and to analyze the relationship with quick sequential organ failure assessment (qSOFA) score and the predictive value on prognosis of patients. Methods: Totally 104 elderly patients with UGB in the hospital from December 2021 to May 2024 were included. The levels of RDW and Hct in the blood of patients were measured, and the association between changes of the two indexes and qSOFA score and prognosis of patients was observed. Results: The RDW level, qSOFA score, age and proportion of bleeding volume≥1000 mL in elderly UGB patients with poor prognosis were higher than those in patients with good prognosis while the Hct was lower than that in patients with good prognosis, with statistical differences (P<0.05). Logistic regression analysis showed that RDW, qSOFA score and blood loss volume≥1000 mL are the risk factors affecting the poor prognosis of elderly UGB patients, and Hct was a protective factor, and the associations were statistically significant (P<0.05). Spearman correlation analysis indicated that RDW level in elderly UGB patients was positively correlated with qSOFA score, and Hct was negatively correlated with qSOFA score, with statistical correlations (r=0.207, -0.197, P<0.05). ROC curve demonstrated that the AUCs of RDW and Hct in evaluating the poor prognosis of elderly UGB patients were 0.731 and 0.777, respectively, while the AUC of RDW+Hct in assessing the poor prognosis was 0.845, higher than AUC of RDW and Hct, and the difference was statistically significant (P<0.05). The sensitivity and specificity under the maximum Youden index were 0.724 and 0.827, respectively. Conclusion: The increase of RDW and decrease of Hct in elderly UGB patients are related to the qSOFA score and prognosis of patients, and the levels of RDW and Hct have certain evaluated value on the poor prognosis of patients.
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2025, Vol. 31 
