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| Effects of General Anesthesia and Epidural Anesthesia on Postoperative Cognitive Function in Elderly Patients with Orthopaedic Surgery |
| SUN Yu, et al |
| Medicine College of Tongji University, Shanghai baoshan district benevolence and hospital, Shanghai baoshan 200431, China |
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Abstract Objective: To observe and compare the general anesthesia and epidural anesthesia effects on short-term cognitive function in elderly patients with orthopaedic surgery. methods: 95 cases of orthopedic surgery elderly patients were randomly divided into two groups: control group (n = 47) line of general anaesthesia, the observation group (n = 48) line of epidural anaesthesia, the anesthesia of arterial blood pressure and heart rate, open and tube drawing and response time, contrast before anesthesia, after anesthesia, 6 h, 12 h, 24 h, 72 h of simple mental health scale (MMSE) score, statistics of two groups of patients with postoperative cognitive dysfunction (POCD) were compared before and after anesthesia. Results: For the arterial blood pressure, heart rate, there was no significant difference between the two groups before and after anesthesia, during operation, 30min, and at the end of the operation (P > 0.05); For opening eyes timing, extubation and response time, there was no significant difference (P > 0.05); The 24h score of MMSE in the observation group was higher than that in the control group (P < 0.05); The POCD incidence rate of 6h and 12h in the observation group was lower than that in the control group (P < 0.05). Conclusion: Compared with general anesthesia, the effect of epidural anesthesia on postoperative cognitive function in elderly patients with Department of orthopedics is more slight.
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2017, Vol. 23 
