Comparison of Short-Term Efficacy and Aesthetics of Breast Tumor Plastic Breast-Conserving Surgery and Extended Resection Breast-Conserving Surgery in the Treatment of Early Breast Cancer
ZHANG Yi, CHEN Yao, WANG Jing
The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Xi'an 710061, China
Abstract：Objective: To compare the influence of breast tumor plastic breast-conserving surgery and extended resection breast-conserving surgery on short-term efficacy and wound aesthetics in patients with early breast cancer. Methods: The clinical data of patients with early breast cancer in the hospital were retrospectively analyzed from January 2021 to January 2024. Fourty-six effective cases were randomly selected from patients undergoing breast tumor plastic breast-conserving surgery and included in group A, and another fourty-six effective cases were randomly collected from patients with extended resection breast-conserving surgery and enrolled as group B. The surgical indicators, short-term efficacy and incidence rates of postoperative complications were compared between groups. The breast aesthetics at 6 months after surgery and levels of tumor serum markers [CA153, heat shock protein 90 A (HSP90 A), osteopontin (OPN), secretory leukocyte protease inhibitor (SLPI)] and quality of life [Functional Assessment of Cancer Therapy-Breast (FACT-B)] before surgery and at 6 months after surgery were recorded. Results: The surgical time, intraoperative blood loss and intraoperative drainage volume in group A were significantly shorter or less than those in group B, and the incision length was significantly shorter than that in group B (all P<0.05). At 6 months after surgery, there was no statistical significance in objective response rate (ORR) between groups (P>0.05). The breast aesthetic rate in group A (58.70%) was significantly higher than that in group B (36.96%) (P<0.05). The levels of serum tumor markers in the two groups were lower than those before surgery (P<0.05), but there was no statistical difference between groups (P>0.05). At 6 months after surgery, the FACT-B scores were higher in both groups than before surgery, and group A had higher scores than group B (all P<0.05). The total incidence rate of complications in group A (19.57%) was lower than that in group B (39.13%) (P<0.05). Conclusion: Breast tumor plastic breast-conserving surgery and extended resection breast-conserving surgery have similar efficacy, but plastic breast-conserving surgery can more effectively improve postoperative breast aesthetics and quality of life of patients, and reduce the incidence rates of postoperative complications. It is suggested to choose the appropriate surgical method for treatment based on the actual situation and the needs of patients in clinical application.
张怡, 陈瑶, 王静. 乳腺肿瘤整形保乳术和保留乳房扩大切除术治疗早期乳腺癌的近期疗效及美观度比较[J]. 河北医学, 2025, 31(6): 1010-1016.
ZHANG Yi, CHEN Yao, WANG Jing. Comparison of Short-Term Efficacy and Aesthetics of Breast Tumor Plastic Breast-Conserving Surgery and Extended Resection Breast-Conserving Surgery in the Treatment of Early Breast Cancer. HeBei Med, 2025, 31(6): 1010-1016.
2025, Vol. 31 
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