Analysis of the Efficacy of Percutaneous Nephrostomy Drainage at Different Timing in the Treatment of Upper Urinary Tract Calculi Complicated with Infection
YU Jianhong, ZHANG Wenjuan, WANG Qianlong, et al
The Affiliated Hospital of Gansu Medical College, Gansu Pingliang 744000, China
Abstract：Objective: To analyze the efficacy of percutaneous nephrostomy (PCN) drainage in the treatment of upper urinary tract stones with infection at different timeing. Methods: Totally 102 patients with upper urinary tract calculi and infection in the hospital from October 2019 to October 2024 were divided into 2h group (n=42, PCN drainage within 2h after admission), 12h group (n=34, PCN drainage within 2~12h after admission) and 24h group (n=26, PCN drainage within 12~24h after admission) according to the different timing of PCN drainage. The surgical time, intraoperative blood loss and one-time puncture success rate, and changes of body temperature and infection-related indicators [white blood cell count (WBC), C-reactive protein (CRP), procalcitonin (PCT)] before surgery and at 3 days after operation were compared among the three groups. The infection control time, hospitalization time and complications in the three groups were recorded. Results: There were no statistical differences in surgical time, intraoperative blood loss and success rate of one-time puncture among the three groups (P>0.05). The hospitalization time in the 2h and 12h groups was shorter than that in the 24h group (P<0.05), but no statistical differences were observed in infection control time and hospitalization time between the 2h group and the 12 h group (P>0.05). At 3 days after surgery, the body temperature, WBC, CRP and PCT in the three groups were lower than those before surgery (P<0.05), and the above indicators in the 24h group were higher than those in the 2h group and the 12h group (P<0.05), but the above indicators were not statistically different between the 2h group and the 12h group (P>0.05). The complications revealed no statistical differences among the three groups (P>0.05). Conclusion: PCN drainage within 12h after admission is effective in the treatment of patients with upper urinary tract calculi and infection, and it can effectively control infection and shorten hospitalization time.
于建宏, 张文娟, 王乾龙, 王磊. 不同时机行经皮肾穿刺造瘘术引流治疗上尿路结石伴感染的效果分析[J]. 河北医学, 2025, 31(8): 1338-1343.
YU Jianhong, ZHANG Wenjuan, WANG Qianlong, et al. Analysis of the Efficacy of Percutaneous Nephrostomy Drainage at Different Timing in the Treatment of Upper Urinary Tract Calculi Complicated with Infection. HeBei Med, 2025, 31(8): 1338-1343.
2025, Vol. 31 
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