Comparison of Efficacy and Complications between Modified LIFT Procedure and Incision-Thread-Drawing Procedure in the Treatment of Trans-Sphincter Anal Fistula
WANG Lu, DANG Wei, QU Bo
Bayin'guoleng Mongol Autonomous Prefecture People's Hospital, Xinjiang Bayin'guoleng 841000, China
Abstract：Objective: To compare efficacy and complications between modified ligation of the inter-sphincteric fistula tract (LIFT) procedure and incision-thread-drawing procedure in the treatment of trans-sphincter anal fistula. Methods: From December 2022 to June 2024, 96 patients with trans-sphincter anal fistula were selected for the study. Using random number table method, they were divided into the routine group (48 cases) and the observation group (48 cases). The routine group was treated with incision-thread-drawing procedure, while the observation group was treated with modified LIFT procedure. Comparisons were made between groups on clinical efficacy and complications. Results: The total effective rates in the two groups were both 100%. There were no statistically significant differences in anal resting pressure, maximum squeeze pressure, mean duration of motor unit potential (MUP) of internal and external anal sphincter and puborectalis between the two groups before surgery (P>0.05). Compared with preoperative measurements, anal resting pressure, maximum squeeze pressure, and mean duration of MUP of internal and external anal sphincter and puborectalis in both groups decreased at 3 months postoperatively. Additionally, the difference values of above measurements before surgery and at 3 months postoperatively were greater in the routine group than in the observation group (P<0.05). Intraoperative blood loss, wound healing time, and hospital stay of the observation group were less and shorter than those of the routine group (P<0.05). There were statistically significant differences in VAS scores of the two groups on day 1 and at 1 week, and 2 weeks postoperatively in terms of time and interaction effects (P<0.05). At 1 week and 2 weeks postoperatively, the observation group got lower VAS scores (P<0.05). The total complication rate was lower in the observation group (P<0.05), but the recurrence rate was comparable between groups (P>0.05). Conclusion: The incision-thread-drawing procedure and modified LIFT procedure both are effective. Compared with the former, the latter can reduce anal function damage, improve surgery-related indicators, and alleviate postoperative pain, with fewer complications.
王路, 党伟, 曲波. 改良LIFT术与切开挂线术治疗经括约肌型肛瘘的疗效和并发症比较[J]. 河北医学, 2025, 31(10): 1748-1753.
WANG Lu, DANG Wei, QU Bo. Comparison of Efficacy and Complications between Modified LIFT Procedure and Incision-Thread-Drawing Procedure in the Treatment of Trans-Sphincter Anal Fistula. HeBei Med, 2025, 31(10): 1748-1753.
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2025, Vol. 31 
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