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| Comparison the Effect of Different Doses of Dezocine Combined with Ropivacaine in Gynecological Patients with Patient Controlled Epidural Analgesia after Operation |
| KONG Jianzhong, et al |
| The Central Hospital of Dalian, Liaoning Dalian 116033, China |
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Abstract Objective: To compare the effects of different doses of dezocine combined with ropivacaine in gynecological patients with postoperative epidural analgesia, and occurrence of adverse reactions, in order to dezocine combined with ropivacaine in epidural analgesia after gynecological surgery to find the best regimen. methods: From January 2014 to December 2015, 120 cases of gynecologic surgery in our hospital were selected, Four groups were randomly divided into four groups using the program, Statistical analysis of VAS pain score and the incidence of adverse reactions were different. Results: The postoperative VAS pain score of D group was compared with that of group A, the difference was not statistically significant (p>0.05); But B group and C group postoperative VAS pain score than A group postoperative pain scores were significantly lower (P<0.05, P<0.01). The incidence of headache, nausea and skin itching in group C was slightly lower than that in group D, the difference was not statistically significant (p>0.05), but the difference in the incidence of vomiting was statistically significant between the two groups (P<0.05); The incidence of skin itching, nausea, postoperative headache, vomiting and other adverse reactions in group A and group B were lower than that in group D, and the difference was statistically significant (P<0.05, P<0.01). Conclusion: Dezocine combined with ropivacaine in gynecological patients with postoperative epidural analgesia has a good analgesic effect, and with the increasing dose of dezocine analgesia effect is more obvious, but the incidence of adverse reactions was also increased. By changing the dosage of dezocine, and achieve the analgesia requirements or reduce the incidence of adverse reactions of the requirements, to provide personalized combination therapy for different patients.
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2017, Vol. 23 
