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| Efficacy Observation of Budesonide Nasal Spray Combined with Montelukast Sodium in the Treatment of Allergic Rhinitis |
| ZHAN Fei, CHEN Feng |
| Xiangyang Center Hospital Affiliated to Hubei arts and Science College, Hubei Xiangyang 441021, China |
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Abstract Objective: To investigate the efficacy of budesonide nasal spray combined with montelukast sodium in the treatment of allergic rhinitis. Methods: 90 patients with allergic rhinitis admitted in our hospital from September 2013 to May 2015 were randomly divided into two groups (45 in each group). Patients in group A received budesonide plus loratadine , Group B patients given budesonide + montelukast sodium, clinical symptoms score and treatment effect of two groups were compared. Results: The nasal obstruction score (0.81 ± 0.18), nasal itching score (0.61 ± 0.19), sneezing score (0.57 ± 0.15), and nasal discharge score (0.34 ± 0.13) in group A were significantly higher than those in group B (0.56 ± 0.15, 0.46 ± 0.11,0.41 ± 0.12,0.21 ± 0.08), there was significant difference (t = 12.451,9.261,7.051,5.337), with statistical significance (P <0.01); The total effective rate in group A (75.56% ) Was significantly lower than that in group B (93.33%), there was a significant difference (χ2 = 5.414), with statistical significance (P <0.05). Conclusion: Comparing the efficacy of budesonide plus loratadine, budesonide + montelukast sodium is the most effective treatment for allergic rhinitis.
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2018, Vol. 24 
