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| Clinical Efficacy of Heparin combined with Dredge Injection in treatment of Pulmonary Embolismand its Effects on Serum TNI Hcy and D-dimer Levels |
| XIANG Hai, GOU Huijun, LUO Jin, et al |
| Guangyuan Traditional Chinese Medicine Hospital, Sichuan Guangyuan 628000, China |
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Abstract Objective: To investigate the clinical efficacy of heparin combined with Shuxuetong injection in the treatment of pulmonary embolism and its influence on serum troponin I (TNI), homocysteine (Hcy) and D-dimer levels. Methods: 90 patients with pulmonary embolism admitted to our hospital from April 2015 to April 2018 were selected as study objects. All the patients were randomly divided into control group and observation group, with 45 cases in each group. After the examination, the patients in both groups were diagnosed and treated according to the conventional western medical treatment. The patients in the control group were treated with shuxuetong injection, and the observation group was treated with heparin on the basis of the control group. The clinical efficacy of the two groups and the changes of troponin I (TNI), homocysteine (Hcy) and d-dimer levels before and after treatment were observed and analyzed. Results: After treatment, the total clinical efficiency of the observation group was significantly higher than that of the control group (P<0.05). PCO2 and PO2 in both groups were significantly higher than before treatment, and PO2 in the observation group was significantly higher than that in the control group. The serum TNI, Hcy and d-dimer levels of the two groups were significantly decreased after treatment compared with those before treatment, and the serum TNI, Hcy and d-dimer levels of the observation group were significantly lower than those of the control group. There was no significant difference in the occurrence of adverse reactions between the two groups (P>0.05). Conclusion: For patients with pulmonary embolism, the treatment of patients with pulmonary embolism with heparin combined with dredge injection can effectively improve the clinical efficacy and significantly reduce the levels of serum troponin I, homocysteine and d-dimer.
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2019, Vol. 25 
