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| Comparative Study of Clinical Efficacy of Autologous Platelet-rich Geland Conventional Dressing Change in Refractory Diabetic Foot |
| ZHOU Lili, XIE Wenqing, XIA Huichang, et al |
| Second People’s Hospital of Foshan Endocrinology, Guangdong Foshan 528000, China |
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Abstract Objective: To compare the clinical efficacy of autologous platelet-rich gel (APG) and conventional dressing change in refractory diabetic foot (DF). Methods: 60 patients with refractory DF admitted to hospital from March 2017 to March 2019 were randomly divided into observation group (standard treatment+APG, n=30) and control group (standard treatment+conventional treatment, n=30). The treatment effects were compared between the two groups. Results: After 2 weeks, 4 weeks and 8 weeks of treatment, the ulcer area in the two groups was decreased in turn, and the difference between the two groups was significant (P<0.05), and the ulcer area in observation group after 2 weeks,4 weeks and 8 weeks of treatment was smaller than that in control group(P<0.05). The treatment effects in observation group were significantly better than those in control group(P<0.05). The ulcer healing time and hospital stay in observation group were significantly shorter than those in control group (P<0.05). During treatment, the incidence rate of adverse reactions in observation group was significantly lower than that in control group (P<0.05). Conclusion: APG combined with standard therapy can effectively improve the healing effect of ulcer in refractory DF patients.
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[1] 晋溶辰,黄政德,张晋如,等.糖尿病足溃疡高危体质的临床特征及对伤口愈合影响的研究[J].湖南中医药大学学报,2016,36(4):56~59.
[2] 罗士欢.糖尿病足溃疡全面治疗的研究现状[J].临床医药文献电子杂志,2016,3(40):8074.
[3] 袁平乔,杨蓉,袁丽.糖尿病患者高危足现状与相关因素分析[J].上海护理,2018,18(11):69~72.
[4] 邸铁涛.细胞生长因子影响糖尿病足溃疡愈合及治疗研究进展[J].贵州医药,2017,41(1):94~96.
[5] 肖赫,李雅嘉,王华,等.纤维连接蛋白在糖尿病足溃疡中的研究进展[J].中国老年学杂志,2017,37(21):5474~5476. |
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2019, Vol. 25 
