术前白细胞衍生性指标对肝癌介入术后早期复发的预测价值研究

doi:10.3969/j.issn.1006-6233.2024.09.027

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Abstract Objective: To analyze the predictive value of preoperative leukocyte-derived indicators on early recurrence of liver cancer after interventional surgery.Methods: Totally 216 patients who underwent interventional surgery for liver cancer in the hospital were included in the study from January 2020 to January 2023. They were followed up for 1 year after surgery and were divided into a recurrence group (n=110) and a non-recurrence group (n=106) according to the recurrence status. Leukocyte-derived indicators of all study subjects were measured before surgery, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR). Subject operating characteristic curve (ROC) was performed to analyze the predictive value of preoperative levels of NLR, PLR, and LMR on early recurrence after interventional surgery for liver cancer.Results: The preoperative NLR and PLR levels in the recurrence group were higher than those in the non-recurrence group while the LMR level was lower than in the non-recurrence group (P<0.05). ROC curve analysis results showed that the area under the curve (AUC) of a combination of preoperative NLR, PLR, and LMR in predicting early recurrence after liver cancer interventional surgery was 0.958, with a sensitivity of 82.73% and a specificity of 95.28%. The efficiency of combined prediction was better than that of each indicator (P<0.05). Conclusion: Preoperative leukocyte-derived indicators are closely related to early recurrence of liver cancer after interventional surgery. Preoperative measurement of NLR, PLR, and LMR levels can predict early recurrence after liver cancer interventional surgery, and provide a certain reference basis for guiding clinical treatment.

Key words： Hepatocellular carcinoma intervention Neutrophil-to-lymphocyte ratio Platelet-to-lymphocyte ratio Lymphocyte-to-monocyte ratio

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	CHEN Shu
	JI Jiuwei
	LIU Xiaoyu
	et al

Cite this article:

CHEN Shu,JI Jiuwei,LIU Xiaoyu, et al. A Study on the Predictive Value of Preoperative Leukocyte Derivativeness Index for Early Recurrence after Hepatocellular Carcinoma Intervention[J]. HeBei Med, 2024, 30(9): 1555-1559.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2024.09.027 OR http://www.hbyxzzs.cn/EN/Y2024/V30/I9/1555

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