基于子宫动脉血流参数的Logistic回归模型在妊娠期高血压患者不良分娩结局的预测价值

doi:10.3969/j.issn.1006-6233.2024.12.024

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Abstract Objective: To explore the predictive value of Logistic regression model of uterine artery blood flow parameters on the adverse delivery outcomes in patients with hypertensive disorder of pregnancy (HDP).Methods: A total of 203 HDP patients who received prenatal examination in the hospital from April 2022 to June 2023 were selected as the study subjects (HDP group), and 100 pregnant women without abortion history were included in control group. All pregnant women were tested for uterine artery blood flow parameters in the second trimester.The pulsatility index (PI), resistance index (RI), and the ratio of peak systolic velocity to diastolic velocity (S/D) were assessed. Independent predictors of adverse delivery outcomes were identified using logistic regression analysis. The effectiveness of the logistic model in predicting outcomes was evaluated through receiver operating characteristic (ROC) curve analysis.Results: The PI, RI and S/D in HDP group were significantly higher than those in control group (P<0.05). Among the 203 patients with HDP, 135 cases had adverse pregnancy outcomes, with the incidence rate of 66.50%. Logistic regression model showed that PI, RI, S/D ratio were independent risk factors for adverse delivery outcomes in HDP patients (P<0.05). The AUC, SE and 95%CI of logistic regression model based on uterine artery blood flow parameters were 0.952, 0.324 and 0.913-0.977 in predicting the adverse delivery outcomes (P<0.001), and the sensitivity, specificity and Youden indexes were 0.896, 0.956 and 0.852.Conclusion: Uterine artery blood flow parameters are of great significance in predicting the risk of adverse delivery outcomes in patients with HDP, and can be used as an effective tool for clinical risk assessment.

Key words： Hypertensive disorder of pregnancy Uterine artery blood flow parameters Logistic regression model Adverse delivery outcomes Prediction model

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2024.12.024 OR http://www.hbyxzzs.cn/EN/Y2024/V30/I12/2069

[1] Lindley KJ,Davila-Roman VG.Microvascular dysfunction in hypertensive disorders of pregnancy:implications for evaluation,treatment,and further research[J].Circ Cardiovasc Imaging,2024,17(5):16816.
[2] 韦唯,汤晶,杜薇娜.妊娠期高血压疾病孕早期风险因素的主成分、聚类及预测价值分析[J].国际检验医学杂志,2024,45(8):964-968.
[3] Dixit S,Dixit NA,Rawat A,et al.Color Doppler ultrasound in high-low risk pregnancies and its relationship to fetal outcomes:a cross-sectional study[J].Front Pediatr,2024,20(11):1221766.
[4] Marsosi V,Haghighi L,Nasimi PH,et al.Effects of sildenafil on Doppler parameters,maternal and neonatal outcomes in the active labor phase of low-risk pregnancies:a randomized clinical trial[J].Perinat Med,2023,52(2):210-214.
[5] Wang H,Iwama N,Yuwaki K,et al.Relationship between parity and the prevalence of chronic kidney disease in Japan considering hypertensive disorders of pregnancy and body mass index [J].BMC Nephrol,2024,25(1):166.
[6] 刘洋,赵巧棉,李海燕,等.miR-181b miR-210miR-126在妊娠期高血压疾病中的表达及与炎症反应的相关性[J].河北医学,2024,30(1):147-152.
[7] Fournier SB,D'Errico JN,Stapleton PA.Uterine vascular control preconception and during pregnancy[J].Compr Physiol,2021,11(3):1871-1893.
[8] 江璐,德丽娜尔·乌尔肯别克,毛新敏,等.孕三烯酮联合醋酸亮丙瑞林治疗对子宫内膜异位症患者生殖激素水平,子宫动脉血流参数以及妊娠率的影响[J].中华保健医学杂志,2023,25(4):411-414.
[9] Lian X,Pan Z,Xia F,et al.Analysis of the guidance and predictive value of uterine artery flow parameters in patients with recurrent spontaneous abortion[J].Obstet Gynaecol Res,2023,49(3):803-811.
[10] 王玮,高华,陆芬芳,等.血管阻力及子宫动脉血流参数预测早期妊娠期高血压疾病并发先兆子痫的效能分析[J].中国妇幼保健,2023,38(02):234-237.