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Study on the Correlation between Chemerin and CRP and Gestational Diabetes |
LIAN Hang, et al |
The Central Hospital of Tongchuan Mining Bureau, Shaanxi Tongchuan 727000, China |
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Abstract Objective: To discuss the levels and clinical significance of chemerin and CRP in the serum of gestational diabetes patients. Methods: From March 2016 to February 2017, 100 suspected gestational diabetes women were selected. According to the diagnosis of gestational diabetes, all women were divided into diabetes group (40 cases) and non-diabetic group (60 cases). At the same time, 50 cases of healthy non-pregnant women were selected as control group. The serum chemerin and CRP expression levels of all subjects were tested by enzyme-linked immunosorbent assay and its clinical significance was discussed. Results: Comparison of serum chemerin, CRP, FBG, 1h FBG, 2 hFBG and 3 hFBG levels in the control group and non-diabetic group, the difference was not statistically significant (P>0.05). The serum chemerin, CRP, FBG, 1h FBG, 2 hFBG and 3 hFBG levels of the diabetic group were all high non-diabetic group, and the difference was statistically significant (P<0.05). The results of ROC curve analysis showed that serum chemerin and CRP level diagnosis of gestational diabetes had good evaluation value. Conclusions: The serum chemerin and CRP in gestational diabetes are at a high level, and the detection of serum chemerin and CRP in pregnant women has certain clinical value in the diagnosis of gestational diabetes.
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