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| Clinical Study of Retcam Ⅲ in the Diagnosis of Neonatal Retinoblastoma by Retinal Imaging System |
| DAN Yanping, CHEN Qingran, RAO Li |
| Shiyan Maternal and Child Health-Care Hospital, Hubei Shiyan 442000, China |
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Abstract Objective: To analyze the clinical value of Retcam III in the early diagnosis of neonatal retinoblastoma using retinal imaging system. Methods: A retrospective analysis was carried out from July 2014 to July 2016 in 75 cases of RB newborns in our department of Ophthalmology and 100 cases of eyes. These patients were treated with binocular indirect ophthalmoscope, RetCam III and B type ultrasonic diagnosis RB. Results: 100 eyes were diagnosed with a double eye ophthalmoscope for the gold standard to diagnose the AE phase of the eye condition, the use of RetCam III diagnosis in the A phase is consistent, B, C, D and E there was a small difference, but very close (P> 0.05). Through the analysis of the Kappa coefficient, the 2 kinds of RB staging are consistent, of which the Kappa coefficient was =0.9794, and the 95% confidence interval was 0.9598-0.9991. In 100 eyes, there were 58 eyes in the A-D period. Using binocular ophthalmoscope 132 standard tumor were detected by RetCam, III in the detection of tumor 130, the detection rate was 98.48%. 111 tumor bodies were detected by B type ultrasound, and the detection rate was 84.09% (P<0.05). RetCam III detection occurred in 2 cases of subconjunctival hemorrhage, the incidence rate was 2%, but there was no adverse reaction in corneal contusion, retinal hemorrhage and infection. The overall bad rate was 2%. The binocular ophthalmoscope and B ultrasonic in the above adverse complications were higher, no difference (P>0.05). This reveals that RetCam III is safe, reliable, and has good prognosis, and is worthy of clinical application. Conclusion: The early diagnosis of neonatal retinoblastoma by Retcam III (retina imaging system) can be used to diagnose the tumor staging and disease in a timely and accurate way. It has high specificity and detection rate, and has high diagnostic value in clinical.
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2018, Vol. 24 
