血浆脑利钠肽在小儿川崎病中的变化及其与心功能的相关性分析

doi:10.3969/j.issn.1006-6233.2018.03.021

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Abstract Objective: To investigate the changes of plasma brain natriuretic peptide in children with Kawasaki disease and its correlation with cardiac function. Methods: From July 2015 to July 2017 in our hospital, 39 cases of pediatric children with Kawasaki disease as the observation group, according to the disease is divided into 20 cases of acute children, 19 cases of convalescent patients; the same period in our hospital 50 cases of healthy children as a control group. The levels of plasma brain natriuretic peptide were detected in the two groups. Meanwhile, the cardiac function indexes in the observation group were also examined. The correlation between plasma brain natriuretic peptide and cardiac function was analyzed. Results: The levels of plasma brain natriuretic peptide in acute stage were significantly higher than those in recovery stage and control group (P <0.05). The level of plasma natriuretic peptide in convalescent group was higher than that in control group, the difference was statistically significant (P <0.05).The indexes of LVSF, CI, LVEF in acute stage were significantly lower than those in recovery stage, the difference was statistically significant (P <0.05). The difference of E / A index and recovery period There was no significant difference between the two groups (P> 0.05). Sodium levels of plasma brain natriuretic peptide and children with acute LVSF, CI, LVEF indicators show a significant negative correlation (P <0.05), and E/A showed no significant correlation (P> 0.05). Conclusion: The level of plasma brain natriuretic peptide in children with acute Kawasaki disease is significantly increased, which is negatively correlated with LVSF, CI and LVEF, which is of great importance for early clinical diagnosis in children.

Key words： Plasma brain natriuretic peptide Pediatric Kawasaki disease Cardiac function

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	SHI Zhengying
	GUAN Jianhong
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Cite this article:

SHI Zhengying,GUAN Jianhong,et al. Analysis of the Changes of Plasma Brain Natriuretic Peptide in children with Kawasaki Disease and its Correlation with Heart Function[J]. HeBei Med, 2018, 24(3): 430-433.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2018.03.021 OR http://www.hbyxzzs.cn/EN/Y2018/V24/I3/430

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