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| Quantitative EEG Features Associated with Poor Prognosis in Patients with Hypertensive Intracerebral Hemorrhage |
| OU Ya, ZHANG Pingshu, YUAN Xiaodong, et al |
| Kailuan General Hospital, Hebei Tangshan 063000, China |
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Abstract Objective: To investigate the quantitative EEG (qEEG) features associated with poor prognosis in patients with hypertensive intracerebral hemorrhage (HICH). Methods: A prospective study was conducted, continuously enrolling 69 patients with HICH from the intensive care unit of the Department of Neurology, Kailuan General Hospital, between January 2017 and June 2023. Based on the modified Rankin score (mRS) at 30 days post-discharge, patients were divided into two groups: the good prognosis group (mRS ≤ 2) and the poor prognosis group (mRS 3-6). General patient data and qEEG monitoring parameters, including alpha, theta, delta, and beta wave power values in the left and right frontal (Fp1, Fp2), frontal (F3, F4), central (C3, C4), parietal (P3, P4), occipital (O1, O2), anterior temporal (F7, F8), mid-temporal (T3, T4), and posterior temporal (T5, T6) regions, were collected. Results: The mean age in the poor prognosis group was significantly higher than in the good prognosis group (P<0.05). The delta wave power in the Fp2, F4, C4, P4, F7-8, and T4 regions in the poor prognosis group was significantly higher than in the good prognosis group (P<0.05). The theta wave power in the Fp1-2, F3, C3, P4, O1, F7, and T3 regions in the poor prognosis group was significantly higher than in the good prognosis group (P<0.05). The overall slow wave index power, including delta and theta waves, in the Fp1-2, F3-4, C3-4, P3-4, O1, F7-8, T4, and whole-brain average slow wave index in the poor prognosis group was significantly higher than in the good prognosis group (P<0.05). Conclusion: Patients with poor prognosis following hypertensive intracerebral hemorrhage show significantly increased delta, theta, and whole-brain average slow wave index power values on qEEG.
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2024, Vol. 30 
