3D重建技术指导下的精准肝切除术治疗儿童肝脏间叶性错构瘤的效果与安全性分析

doi:10.3969/j.issn.1006-6233.2025.02.017

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Abstract Objective: To evaluate the clinical value of 3D reconstruction technique-precision hepatectomy in the treatment of mesenchymal hamartoma of liver (MHL) in children. Methods: A total of 102 children with MHL in our hospital from January 2019 to May 2023 were randomized 1:1 to conventional precise hepatectomy (conventional group) or 3D reconstruction technique-precision hepatectomy(3D group). The surgical indexes, inflammatory stress indexes (Interleukin-6 [IL-6]), Tumor necrosis factor-α [TNF-α], C-reactive protein [CRP]), liver function indexes (alanine aminotransferase [ALT, aspartate aminotransferase [AST], total bilirubin [BIL], direct bilirubin [DBIL], indirect bilirubin [IBIL]),Visual Analogue scale (VAS)for postoperative pain, quality-of-life (QOL) scores, and complication rate, were included as comparisons before and after surgery between groups. The recurrence rate of the two groups following 1-year follow-up was assessed. Results: The amount of blood loss in the 3D group was statistically less than that in the conventional group, the time to operation, time to hepatic artery occlusion and hospital stay were significantly shorter than those in the conventional group (P<0.05). The levels of CRP, IL-6, TNF-α, AST, ALT, TBIL, DBIL, and IBIL in 3D groups at 1, 3 and 7 days of surgery were significantly lower than those in conventional group (P<0.05).The VAS scores at 12 h, 24 h, 48 h and 72 h in the 3D group were significantly lower than those in the conventional group (P<0.05). After 3 months of surgery, the QLL scores in 3D group were significantly higher than those in conventional group (P<0.05). The complication rate of 3D group was significantly lower than that of conventional group (3.92% vs 17.65%, P<0.05). There was no significant difference in the recurrence rate between the two groups at 1 year of follow-up (P>0.05). Conclusion: The 3D reconstruction technology-guided precise hepatectomy in the treatment of pediatric MHL can optimize the surgery, reduce inflammatory response and pain degree, promote postoperative recovery, improve liver function, reduce complications, and improve quality of life, with a confirmed long-term efficacy.

Key words： Mesenchymal hamartoma Liver Hepatectomy 3D reconstruction technology

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	HUANG Baisha
	HUANG Yiwen
	DONG Chou

Cite this article:

HUANG Baisha,HUANG Yiwen,DONG Chou. Effect and Safety Analysis of 3D Reconstruction Technique- guided Precise Hepatectomy on Mesenchymal Hamartoma of Liver in Children[J]. HeBei Med, 2025, 31(2): 274-281.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2025.02.017 OR http://www.hbyxzzs.cn/EN/Y2025/V31/I2/274

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