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| The Effect of Escitalopram on the Neurologic Function and Cognitive Function of the Post-stroke Depression Patients |
| HU Huiting, WANG Minzhong |
| The Affiliated Provincial Hospital of Shandong University, Shandong Ji'nan 250021, China |
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Abstract Objective: To explore the effect of Ai Sciplan on the neural function and cognitive function of patients with post-stroke depression. Methods: 82 stroke patients were selected in our hospital from October 2016 to October 2017 were patients with depression as the research object, it was divided into study group ( 41 cases ) and control group ( 41 cases ) by random number table method , two groups of patients were treated with routine drug treatment the study group, patients taking escitalopram on the basis of routine therapy, patients in control group received placebo on the basis of conventional drug treatment, continuous treatment for 12 weeks. The depression of two groups were compared before and after treatment, nerve function, the cognitive function and life ability The evaluation. Results: Before treatment, there was no significant difference in the HAMD score, NIHSS score, MMSE score and FIM score between the two groups (P>0.05). After treatment, the HAMD scores, NIHSS scores, MMSE scores and FIM scores of the two groups were all improved, and the observation group was significantly better than the control group (P<0.05). Conclusion: In the clinical treatment of post-stroke depression, the use of escitalopram can improve neurological function and cognitive function, as well as improve depression and viability of patients.
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2018, Vol. 24 
