脾切除贲门周围血管离断术治疗肝硬化门脉高压症的疗效及对患者肝功能指标的影响

doi:10.3969/j.issn.1006-6233.2018.03.006

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Abstract Objective: To explore the effect of splenectomy and pericardial devascularization in the treatment of portal hypertension with liver cirrhosis and its effect on liver function in patients. Methods: A total of 78 patients with portal hypertension were treated in our hospital from March 2016 to May 2017. All the patients were divided into two groups according to random number table, each group of 39 cases. The patients in the control group were treated with traditional open splenectomy and pericardial devascularization. And the patients in the observation group were treated with laparoscopic splenectomy and pericardial devascularization. The clinical indicators, liver function indexes and complications were compared between the two groups. Results: The intraoperative blood loss, visual analogue scale (VAS) score, bowel function recovery time and hospitalization time were less in the observation group, and the operation time was longer and the difference was statistically significant(P <0.05).There was no significant difference in the levels of prothrombin time (PT), albumin (ALB), alanine aminotransferase (ALT) and total bilirubin (TBIL) between the two groups before operation (P> 0.05).The levels of PT, ALB, ALT and TBIL in the two groups were significantly better than those before operation (P <0.05).The levels of PT, ALT and TBIL in the observation group were significantly higher than those in the control group, the ALB level was lower (P <0.05).The incidence of postoperative complications was 5.13% (2/39) in the observation group significantly higher than that in the control group (23.08%, 9/39), the difference was statistically significant (P <0.05). Conclusion: Laparoscopic resection of pericardial cardiomyocytes can reduce the amount of intraoperative blood loss, reduce the incidence of complications, shorten the recovery time and hospital stay in patients with cirrhotic portal hypertension, improve liver function.

Key words： Splenectomy Pericardial devascularization Cirrhosis portal hypertension Liver function index

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XIE Xiang,et al. Effect of Splenectomy and Pericardial Devascularization in the Treatment of Hepatocirrhosis with Portal Hypertension and the Influence on Liver Function of Patients[J]. HeBei Med, 2018, 24(3): 374-378.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2018.03.006 OR http://www.hbyxzzs.cn/EN/Y2018/V24/I3/374

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