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| Relationship between NEU/ALB Hemodynamics, Immunoglobulins and Renal Function Outcome in Elderly Patients with Infection-Induced Acute Kidney Injury |
| XIE Juan, NI Gang, PAN Yachao, et al |
| Hefei First People's Hospital, Anhui Hefei 230000, China |
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Abstract Objective: To investigate the relationship of neutrophil (NEU)/albumin (ALB), hemodynamics and immunoglobulins levels with renal function outcome in elderly patients with infection-induced acute kidney injury (AKI). Methods: Totally 117 elderly patients with infection-induced AKI in the hospital were selected from January 2021 to December 2023 as the research subjects. NEU, ALB, hemodynamics and immunoglobulin were detected at admission. The patients were treated with comprehensive symptomatic treatment and were divided into good outcome group and poor outcome group according to the outcome of renal function. The levels of NEU/ALB, hemodynamics and immunoglobulins were compared between groups. Multivariate Logistic regression analysis was used to analyze the influencing factors of renal function outcome in elderly patients with infection-induced AKI. Results: There were no statistical differences in gender, age, body mass index (BMI) and urinary protein between the good outcome group and the poor outcome group (P>0.05), but serum creatinine level was lower than that in the poor outcome group (P<0.05). NEU and NEU/ALB in the good outcome group were lower than those in the poor outcome group (P<0.05) while ALB, IgG and IgM levels were higher (P<0.05), and MAP and CI were higher than those in the poor outcome group (P<0.05), but the HR and IgA were not statistically different compared with those in the poor outcome group (P>0.05). Multivariate Logistic regression analysis showed that NEU/ALB, MAP, CI and IgG were influencing factors of renal function outcome in elderly patients with infection-induced AKI (P<0.05). Conclusion: The NEU/ALB, hemodynamics and immunoglobulins levels are correlated with renal function outcome in elderly patients with infection-induced acute kidney injury. The detection of the above indicators is helpful to evaluate the renal function outcome of patients.
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2024, Vol. 30 
