老年肌少症与吞咽功能障碍发生的关系及高压氧辅助治疗效果观察

doi:10.3969/j.issn.1006-6233.2025.05.018

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Abstract Objective: To observe the relationship between elderly sarcopenia and swallowing dysfunction and analyze the effect of hyperbaric oxygen (HBO) adjuvant therapy. Methods: Totally 120 elderly patients with sarcopenia in the hospital from January 2022 to December 2023 were selected as the research subjects, and they received water swallow test. The occurrence of swallowing dysfunction was observed. The elderly patients with sarcopenia complicated with swallowing dysfunction were randomized into two groups. The control group adopted neuromuscular electrical stimulation, whereas the observation group received HBO adjuvant therapy on the basis of the control group. The levels of serum nutritional indexes [albumin (ALB), transferrin (TF)], modified Mann assessment of swallowing ability (MMASA), functional oral intake scale (FOIS) and swallowing-quality of life questionnaire (SWAL-QOL) were compared between groups at different time points. Results: Among the 120 elderly patients with sarcopenia, 66 cases were combined with dysphagia, the detection rate was 55.00%. 66 elderly patients with sarcopenia complicated with swallowing dysfunction were divided into control group (n=33) and observation group (n=33) by simple randomization method. At 3 weeks of treatment and at the end of treatment, serum ALB and TF levels in both groups were risen compared with those before treatment (P<0.05). The level of serum ALB in the observation group was higher than that in the control group at 3 weeks of treatment (P<0.05), and serum TF level was not statistically different from that in the control group (P>0.05), and the levels of serum ALB and TF at the end of treatment were higher compared with those in the control group (P<0.05). The swallowing function-related scores (MMASA, FOIS, SWAL-QOL) in both groups were enhanced at 3 weeks of treatment and at the end of treatment compared with those before treatment, and the observation group had higher scores (P<0.05). Conclusion: Elderly patients with sarcopenia are prone to swallowing dysfunction. After HBO adjuvant therapy, the swallowing function and nutritional status of elderly sarcopenia patients with swallowing dysfunction are significantly improved.

Key words： Elderly sarcopenia Swallowing dysfunction Hyperbaric oxygen Efficacy

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2025.05.018 OR http://www.hbyxzzs.cn/EN/Y2025/V31/I5/806

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