Abstract：Objective: To analyze the risk factors affecting maxillofacial gap infection after oral trauma. Methods: The clinical data of 115 patients with maxillofacial gap infection after oral trauma in the hospital from January 2020 to January 2024 were retrospectively analyzed and the patients were included in infection group. The clinical data of 123 patients with non-infection after oral trauma who were treated in the hospital during the same period were retrospectively analyzed and the patients were set as non-infection group. The general data such as gender, age, history of diabetes mellitus, iatrogenic procedure, hormone use and nutritional status, serum inflammatory indexes [D-dimer (D-D), erythrocyte sedimentation rate (ESR), macrophage inflammatory protein-2 (MIP-2), serum amyloid A (SAA), C-reactive protein (CRP), soluble cluster of differentiation 14 subtype (sCD14-ST)] and blood routine indexes [white blood cell count, platelet count, neutrophil count (NEU)] at admission were compared between groups. The risk factors of maxillofacial space infection after oral trauma were analyzed by logistic regression analysis. Results: nivariate analysis showed that age, history of diabetes mellitus, iatrogenic improper procedure, proportion of nutritional status, MIP-2, CRP, sCD14-ST, white blood cell count and NEU had statistically significant differences (P<0.05). After logistic regression analysis, it was found that age>60 years old, history of diabetes mellitus, iatrogenic improper procedure, poor nutritional status and increased MIP-2, CRP, sCD14-ST, white blood cell count and NEU were independent risk factors for maxillofacial space infection after oral trauma (P<0.05). Conclusion: Age>60 years old, concomitant diabetes mellitus, iatrogenic improper procedure, poor nutritional status, MIP-2, CRP, sCD14-ST, white blood cell count and NEU are independent risk factors affecting maxillofacial gap infection after oral trauma
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2025, Vol. 31 
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