Clinical Efficacy Analysis of Rigid Bronchoscopy Combined with Electronic Bronchoscopy for the Interventional Treatment of Malignant Tumours of the Central Airway
LI Changdong, SUN Yong, TANG Yuquan, et al
Anqing Municipal Hospital, Anhui Anqing 246003, China
Abstract：Objective: To explore the clinical efficacy of rigid bronchoscopy combined with electronic bronchoscopy in the interventional treatment of malignant central airway tumors, and to provide a basis for optimizing clinical treatment regimens. Methods: The clinical data of patients with malignant central airway tumors who received bronchoscopic interventional treatment in Anqing Municipal Hospital from February 2020 to February 2025 were retrospectively analyzed. According to the treatment methods, the patients were divided into the combined group (treated with rigid bronchoscopy combined with electronic bronchoscopy) and the single-scope group (treated with electronic bronchoscopy alone). After 1:1 matching using propensity score matching (PSM), 51 patients were finally included in each group. The tumor resection degree, ventilation function improvement indicators [airway stenosis degree, dyspnea index, modified Medical Research Council (mMRC) dyspnea scale, blood gas indicators and pulmonary function indicators], perioperative indicators (operation time, blood loss, length of hospital stay, intraoperative stent implantation rate, complication rate, ICU admission rate and 7-day postoperative reintervention rate), and overall efficacy were compared between the two groups. Results: After PSM, the baseline data of the two groups were balanced and comparable (P>0.05). The complete tumor resection rate in the combined group (78.43%) was higher than that in the single-scope group (50.98%) (P<0.05). At 7 days after operation, the indicators in the combined group, such as airway stenosis degree, dyspnea index, mMRC score, arterial oxygen saturation (SaO2), arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PaCO2), forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and maximal voluntary ventilation (MVV), were better than those in the single-scope group (P<0.05). The operation time and blood loss in the combined group were higher than those in the single-scope group (P<0.05), but the length of hospital stay and 7-day postoperative reintervention rate were lower than those in the single-scope group (P<0.05). The number of people (31/51) who achieved remarkable results in the combined group was higher than that in the single-scope group (16/51). (P<0.05). Conclusion: Rigid bronchoscopy combined with electronic bronchoscopy in the interventional treatment of malignant central airway tumors is superior to electronic bronchoscopy alone in terms of tumor resection effect, ventilation function improvement and perioperative safety. It is an effective treatment strategy and worthy of clinical promotion and application.
李长东, 孙勇, 汤裕泉, 丁国正. 硬质支气管镜联合电子支气管镜介入治疗中央气道恶性肿瘤的临床疗效分析[J]. 河北医学, 2026, 32(2): 315-323.
LI Changdong, SUN Yong, TANG Yuquan, et al. Clinical Efficacy Analysis of Rigid Bronchoscopy Combined with Electronic Bronchoscopy for the Interventional Treatment of Malignant Tumours of the Central Airway. HeBei Med, 2026, 32(2): 315-323.
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2026, Vol. 32 
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