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| Study on the Correlation between Microscopic Appearances and Histopathological Changes of Actinic Keratosis |
| QIN Jun, PI Xiaobing, WANG Xiaoxia, et al |
| The First People's Hospital of Foshan, Guangdong Foshan 528000, China |
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Abstract Objective: To study the skin microscopy and histopathological changes of solar keratosis. Methods: The lesion was examined by histopathological examination, and the skin lesions were observed by SLR camera and skin mirror. Results: 56 cases were diagnosed with suspected kyphotic keratosis patients, of which 46 cases of skin and pathology consistent with the results of solarization keratosis, 10 cases of dermatology diagnosis of solarization keratosis, and histopathological Results:2 cases of basal cell carcinoma, 7 cases of seborrheic keratosis, 1 case of eczema, dermoscopy and pathology coincidence rate was 82.14%. Among them, female patients in 22 cases (47.83%), male patients in 24 cases (52.17%). 6 patients (13.04%) from 51 to 60 years old, 24 patients (52.17%) from 61 to 70 years old, 71~ 82 years old patients in 11 cases (23.92%). Most of the elderly patients, the age of onset concentrated in the 60 to 80 years old, accounting for 74.23% of the number of this study. The longest course of the disease for more than 20 years. There were significant differences in the occupation of the patients, the largest number of farmers, 38 cases (82.61%). There were 6 cases (13.04%) of cervical disease and 3 cases (6.53%) of patients with dorsal disease. There were 6 patients (13.04%) with pain in the affected area, 32 patients (69.57%) with itching, 8 patients (17.39%) without obvious discomfort. Patients with 0.4cm ~ 3.3cm lesions, the performance of red or yellow brown patches or pimples, lesions more dry parts, damage was scaly, and often appear excessive keratosis and verrucous features. Some patients with ulceration of crust injury site symptoms. At the same time, skin lesions around the skin days of sun damage characteristics, such as skin atrophy, pigment changes and significant expansion of blood vessels. Histopathological findings showed that there were 8 cases (17.39%) of hypertrophic patients, 13 cases (28.26%) of atrophic patients and 4 cases (8.70%) of pigment patients, 5 cases of digitated patients (10.87%), Type of bowenoid patients in 13 cases (28.26%), acantholytic type in 3 cases (6.52%). Dermoscopic erythema, under the background of false grid structure in 33 cases (71.74%), hair follicle hornplug surrounded by white circles in 28 cases (60.87%), 25 cases of punctate structures around the hair follicle orifice (54.35%), performance scales in 39 cases (84.78%), showing erythema in 34 cases (73.91%), 36 cases of strawberry the structure of (78.26%), 37 cases had curled vessels (80.43%). Conclusion: There is a good consistency of dermoscopy on the diagnosis of solar keratosis and pathological findings of the results. Sunshine keratosis skin mirror performance and histopathological changes have obvious characteristics, through the relevant examination to diagnose the disease, early treatment, reduce the patient's condition deterioration, the risk of cancer, the detection method worthy of clinical promotion.
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2017, Vol. 23 
