巴曲酶联合银杏叶注射液治疗突发性耳聋的疗效及对患者凝血功能的影响

doi:10.3969/j.issn.1006-6233.2018.06.026

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Abstract Objective: To explore the clinical efficacy and the effect of the injection of baotase combined with ginkgo biloba in patients with sudden deafness. Methods: A total of 143 patients with sudden deafness were randomly divided into control group (n = 71) and treatment group (n = 72). Both groups of patients were treated with ginkgo biloba injection. The treatment group was based on the basic therapy combined with the treatment of balthase, continuous treatment for 2 weeks. After treatment, 2 groups of clinical efficacy were calculated. To detect and compare the changes of the pure acoustic threshold and coagulation function of the two groups before and after treatment. The adverse reactions during the treatment of 2 groups were calculated. Results: The total effective rate of treatment group was 90.28%, significantly higher than 71.83% in the control group (P<0.01). Compared with the treatment before treatment, the pure acoustic threshold of the two groups was significantly reduced after treatment. The treatment group was significantly lower than the control group (P<0.01); After treatment, both PT and APTT were significantly shortened after treatment (P <0.05 or P<0.01). The treatment group was significantly shorter than the control group (P < 0.01); The serum FIB levels were significantly lower in the 2 groups after treatment, and the treatment group was significantly lower than the control group (P<0.01). The serum d-d levels were significantly higher in 2 groups (P <0.05 or P< 0.01), and the treatment group was significantly higher than the control group (P<0.01). The incidence of adverse reactions in the treatment group was 5.56%, which was significantly lower than that in the control group (P < 0.05). Conclusion: The combination of Batroxobin and ginkgo leaf injection can effectively improve hearing and coagulation function in patients with sudden deafness, and reduce the related adverse reactions effectively. The curative effect is significantly better than that of ginkgo leaf injection.

Key words： Sudden deafness Balqu enzyme Ginkgo leaf Coagulation function

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2018.06.026 OR http://www.hbyxzzs.cn/EN/Y2018/V24/I6/979

[1] 张静,李鑫,田理.突发性耳聋中西医治疗进展[J].实用中医药杂志,2016,32(6):627~629.
[2] Zhang X, Xu X, Ma W, et al. A clinical study of sudden deafness[J]. Acta oto-laryngologica, 2015, 135(10): 1~6.
[3] 杨彰斌,洪海裕,郭剑玲,等.长期服用银杏叶片治疗突发性耳聋的远期疗效观察[J].海南医学,2014,25(20):2999~3001.
[4] 董萨莎,陈莉.探讨老年突发性耳聋应用巴曲酶结合长春西汀治疗的临床效果[J].当代医学,2017,23(4):93~94.
[5] 中华医学会耳鼻喉科学会.中华耳鼻咽喉科杂志编辑委员会.突发性耳聋诊断依据和疗效分级标准[J].中华耳鼻咽喉科杂志,1997,32(2):72~74.
[6] Blasco M A, Redleaf M I. Cochlear implantation in unilateral sudden deafness improves tinnitus and speech comprehension: meta-analysis and systematic review[J]. Otology & neurotology, 2014, 35(8): 1426~1432.
[7] 李漫, 沈红强,杨翼,等.针药联合治疗突发性耳聋的疗效观察[J].世界中医药,2011,6(2):104~106.
[8] 巴艳东,徐永和.突发性耳聋的中医病因病机探析[J].内蒙古中医药,2015,34(10):147~148.
[9] 韩倩,渠晓丽,刘平,等.银杏叶提取物对突发性耳聋患者免疫功能的影响及疗效观察[J].临床误诊误治,2015,28(2):106~108.
[10] 王会芳,于彩霞,王家坡,等.巴曲霉治疗突发性耳聋患者凝血功能指标变化的临床意义[J].标记免疫分析与临床,2014,21(6):698~700.
[11] 任玉军.巴曲酶联合银杏达莫对突发性耳聋患者听力及血液流变学的影响[J].海南医学院学报,2016,22(21):2570~2572.
[12] 孙光炎.巴曲酶联合银杏达莫注射液治疗突发性耳聋的临床疗效及安全性分析[J].中国处方药,2017,15(2):96~97.
[13] 李文华,杨盈盈,谢桃,等.巴曲霉联合银杏注射液对突发性耳聋患者凝血功能指标的影响[J].海峡药学,2015,27(10):169~170.