4D数字化弱视斜视矫治系统辅助治疗对屈光参差性弱视患儿视网膜微血流状态及RNFL厚度的影响

doi:10.3969/j.issn.1006-6233.2025.03.015

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Abstract Objective: To compare the influence of adjuvant therapy of 4D digital strabismus and amblyopia visual function correction system (4D-DSAAVFCS) on retinal microcirculation and retinal nerve fiber layer (RNFL) thickness in children with anisometropic amblyopia (AA). Methods: Totally 118 children with AA in the hospital from March 2022 to May 2024 were randomly divided into control group (n=59, conventional therapy) and treatment group (n=59, 4D-DSAAVFCS adjuvant therapy + conventional therapy). The clinical efficacy of the two groups was evaluated. The retinal microcirculation and RNFL thickness before and after treatment were compared between groups, and the rate of stereoscopic acuity converting to normal was evaluated in both groups before and after treatment. Results: The total effective rate in the treatment group was better than that of the control group (P<0.05). Compared with the control group, the blood flow density in superficial capillary plexus (SCP), deep capillary plexus (DCP), and optic blood flow density were significantly increased in the treatment group after treatment (P<0.05). The differences in RNFL thickness of various areas around the optic disc (OD) (nasal, upper and lower) in the treatment group were significantly increased after treatment compared to the control group (P<0.05). After treatment, the rate of stereoscopic acuity converting to normal in patients with abnormal stereoscopic acuity in the treatment group was significantly higher than that of the control group (P<0.05). Conclusion: The adjuvant therapy of 4D-DSAAVFCS has a better efficacy in the treatment of children with AA, and it can more effectively improve the retinal microcirculation, RNFL thickness and visual function of the children compared to conventional therapy.

Key words： Anisometropic amblyopia 4D digital Strabismus and amblyopia visual function correction system Retinal microcirculation Retinal nerve fiber layer

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2025.03.015 OR http://www.hbyxzzs.cn/EN/Y2025/V31/I3/435

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