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| Influence of Sacral Neuromodulation Adjuvant Therapy on Urodynamics and Urinary Tract Infection in Patients with Neurogenic Bladder after Spinal Cord Injury |
| BAI Xiaojing, MA Yafang, CHEN Meng |
| The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Xi'an 710061, China |
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Abstract Objective: To analyze the effect of sacral neuromodulation adjuvant therapy on neurogenic bladder (NB) after spinal cord injury (SCI). Methods: Totally 112 patients with NB after SCI in the hospital from March 2021 to March 2024 were divided into a control group (n=56, conventional treatment) and a treatment group (n=56, sacral neuromodulation adjuvant therapy + conventional treatment) using simple random sampling method. The urodynamic indexes, urination function, occurrence of urinary tract infection (UTI), and quality of life in the two groups were evaluated. Results: After treatment, the residual urine volume in the treatment group was decreased while the maximum bladder capacity and maximum urinary flow rate were increased compared with those in the control group (P<0.05). After treatment, compared with the control group, the daily average urination frequency and daily average urinary incontinence frequency were reduced while the single urination volume was enhanced in the treatment group (P<0.05). The incidence of UTI declined significantly in the treatment group compared to the control group (P<0.05). The scores of dimensions of General Quality of Life Inventory-74 (GQOLI-74) in the treatment group after treatment were higher than those in the control group (P<0.05). Conclusion: The application of sacral neuromodulation adjuvant therapy can improve the urodynamics and urination function, reduce the UTI, and strengthen the quality of life in patients with NB after SCI.
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2025, Vol. 31 
