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| Effect of Breast-Conserving Surgery Combined with Mastoscopic Axillary Lymph Node Dissection on Short-Term and Long-Term Efficacy in Patients with Early Breast Cancer |
| WANG Ya, QI Jing, et al |
| The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Xi'an 710061, China |
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Abstract Objective: To analyze the effect of breast-conserving surgery (BCS) combined with mastoscopic axillary lymph node dissection (MALND) on short-term and long-term efficay in patients with early breast cancer (BC).Methods: A total of 98 BC patients treated between January 2017 and December 2018 were selected, and divided into observation group (BCS combined with MALND) and control group (BCS combined with conventional lymph node dissection) according to the random number table method, with 49 cases in each group. Intraoperative and postoperative indicators, upper limb activities, social fitness, short-term and long-term survival, and complications were compared between the two groups. Results: The operation time and hospital stay of observation group were shorter than those of the control group (P<0.05). The intraoperative blood loss and postoperative drainage volume of observation group were less than those of the control group (P<0.05). There was no significant difference in upper limb activities between the two groups before operation (P>0.05). The ranges of internal rotation, external rotation, adduction, abduction, abduction, anteflexion and retroflexion were reduced at 6 months after operation (P<0.05), and the difference in the ranges of observation group were greater than those of the control group (P<0.05). There was no significant difference in social fitness between the two groups before operation (P>0.05). The Social Adaptation Questionnaire (SAQ) scores and Functional Assessment of Cancer Therapy-Breast (FACT-B) scores were significantly increased at 6 months after operation (P<0.05), and the scores difference in the observation group had higher than the control group (P<0.05). All subjects were followed up, survival analysis showed that the median survival time of observation group and control group was 38 months and 37 months, respectively. There was no statistically significant difference in overall survival between the two groups (P>0.05). The total incidence of complications in the observation group was lower than that in the control group (P<0.05). Conclusion: BCS combined with MALND for treating early BC can shorten the operation time and hospital stay, and promote recovery. It also can improve upper limb activities and the patients’ social fitness after surgery, with few complications.
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2022, Vol. 28 
