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| Application of the Radial Dorsal Digital Artery Perforator Pedicled Propeller Flap in the Repair of Finger Skin Defects Patients and Its Effect on Serum Levels of IL-6 TNF-α and IL-8 |
| LI Shouxi, ZHANG Liangyin, LYU Changju, et al |
| Baiyin First People's Hospital, Gansu Baiyin 730900, China |
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Abstract Objective: To investigate the application effect of perforator pedicled propeller flap (PPPF) with radial dorsal digital artery in repairing skin defects of the fingers and its influence on serum levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and interleukin-8 (IL-8). Methods: A retrospective analysis was conducted on the clinical data of 80 patients with finger skin defects admitted to The 1st People's Hospital of Baiyin from March 2020 to March 2024. According to the surgical plan, they were divided into an observation group (n=40) and a control group (n=40), and underwent radial dorsal finger artery PPPF repair and conventional radial dorsal skin flap repair, respectively. The two groups were statistically analyzed in terms of perioperative indicators, serum IL-6, TNF - α, IL-8 levels, peripheral blood circulation indicators, hand function related indicators, complications, and satisfaction with finger cosmetic procedures. Results: The observation group had a shorter wound healing time, hospitalization time, and antibacterial drug use time than the control group, and a lower two-point discrimination than the control group (P<0.05). The levels of serum IL-6, TNF-α, and IL-8 in the observation group were lower than those in the control group on postoperative days 3 and 7 (P<0.05). At 3 and 6 months post-surgery, the observation group exhibited higher tissue partial pressure of oxygen (TcPO2), blood perfusion, Michigan Hand Function Questionnaire (MHQ) scores, and total finger joint mobility compared to the control group. Additionally, the cold intolerance symptom severity (CISS) score was lower in the observation group than in the control group (P<0.05). The complication rate in the observation group was lower than that in the control group 6 months after surgery, and the cosmetic satisfaction rate of the affected fingers was higher than that in the control group (P<0.05). Conclusion: The use of the radial dorsal digital artery PPPF to repair skin defects in fingers can reduce inflammatory reactions, promote wound healing, improve blood flow in the affected finger, restore hand function, reduce the risk of complications, and improve cosmetic satisfaction in the affected finger.
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2025, Vol. 31 
